Tetracycline-grafted PLGA nanoparticles as bone-targeting drug delivery system
نویسندگان
چکیده
منابع مشابه
Tetracycline-grafted PLGA nanoparticles as bone-targeting drug delivery system
PURPOSE Nanoparticles (NPs) that target bone tissue were developed using poly(lactic-co-glycolic acid) (PLGA) copolymers and tetracycline (TC)-based bone-targeting moieties. These NPs are expected to enable the transport of drugs, such as simvastatin (SIM), for the treatment of osteoporosis. METHODS The molecular structures of TC-PLGA were validated by (1)H-NMR, and the SIM-loaded NPs were pr...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2015
ISSN: 1178-2013
DOI: 10.2147/ijn.s88798